Patient - Acromegaly - Patient Support

Stay informed, connected, and supported
The R.A.R.E.^® program may help with financial assistance and more

The R.A.R.E. Patient Support Program is designed to make it easier for you to get and stay on your treatment

STEPS TO TREATMENT SUCCESS

FINANCIAL ASSISTANCE

Help for uninsured, and patients with high out-of-pocket costs

PHARMACIST FOLLOW-UP

A pharmacist will call to schedule delivery and answer questions

NURSE EDUCATOR CHECK-IN

A specially trained nurse will call to ensure your treatment is off to a good start

WORRY-FREE REFILL PROCESSING

To help you stay on track with treatment

Co-pay program

Recordati Rare Diseases offers a $20 co-pay for qualified patients with commercial insurance.^a

Home injection program

If you are starting treatment with SIGNIFOR LAR, you may be able to participate in our home injection program at no additional cost.

aEligibility requirements, restrictions and limitations apply.

The R.A.R.E. Patient Support Program is administered in partnership with our specialty pharmacy.

CONTACT THE R.A.R.E. PATIENT SUPPORT PROGRAM FOR ASSISTANCE

Monday-Friday between 8:00 AM and 8:00 PM ET:
Phone: 1-888-855-RARE (7273)
A pharmacist is always available.

CONNECT WITH A PATIENT LIAISON (PL)

Your health journey is uniquely your own, but you’re not alone. As part of the Recordati Access, Resources, and Engagement (R.A.R.E.^®) family, you have access to a Recordati Rare Diseases PL to help you with your treatment along the way.

To get started, complete the Program Enrollment Opt-In Form

COMPLETE THE OPT-IN FORM

When you opt in, your PL^b will be there to:

Provide additional disease state education
Answer questions about your medicine^b
Connect to additional resources regarding the disease state
Listen with an empathetic ear

bThese services are provided at no additional cost to you by Recordati Rare Diseases. Information provided by the PL program is for educational purposes only and is not intended to replace the care and advice of your healthcare providers.

Find Resources to help ON Your treatment Journey

Important Safety Information:

High blood sugar (hyperglycemia), diabetes, and increased ketones in your urine or blood (ketoacidosis): SIGNIFOR LAR can cause serious side effects such as high blood sugar (hyperglycemia), diabetes, and ketoacidosis. Your healthcare provider should check your blood sugar level before you start receiving SIGNIFOR LAR and while you receive it. Tell your healthcare provider right away if you have any of these symptoms: feel very thirsty, urinate more than usual, nausea, vomiting, abdominal pain, increased appetite with weight loss, tiredness, fruity scented breath, trouble breathing, and/or confusion. If you get hyperglycemia, your healthcare provider may give you medicine to lower your blood sugar and/or change your dose of SIGNIFOR LAR or advise you to stop receiving it.

Important Safety Information:

Slow heart rate (bradycardia) and changes in the electrical system of your heart (QT Prolongation): SIGNIFOR LAR can cause your heart to beat slower, which can cause you to feel weak, dizzy, or even faint. People who have, or have had, heart problems, are at greater risk for bradycardia. Abnormal heart beats, weakness, dizziness, and fainting spells may occur due to problems with the electrical system of the heart and can be serious. Call your doctor right away if you experience such spells.

Liver Test Elevations: SIGNIFOR LAR can cause higher than normal liver function tests. Your healthcare provider should do blood tests to check your liver while you receive SIGNIFOR LAR.

Gallstones (cholelithiasis) and complications that can happen if you have gallstones: Gallstones are a serious but common side effect of SIGNIFOR LAR. Your healthcare provider should do a test (ultrasound) to check your gall bladder before and during your treatment.

Low levels of pituitary hormones (pituitary insufficiency): SIGNIFOR LAR reduces the pituitary hormones in your body. Your healthcare provider should do a blood test to check your pituitary hormone levels before you start receiving SIGNIFOR LAR and while you receive it.

Most common side effects of SIGNIFOR LAR include: diarrhea; headache; stomach-area pain; hair loss; stuffy nose and sore throat; low blood sugar; limb swelling; loss of appetite; nausea; increase in the level of the enzyme in your blood called creatine phosphokinase (CPK); tiredness; stomach bloating, high blood pressure; back pain. These are not all the possible side effects of SIGNIFOR LAR. For more information, ask your healthcare provider.

To report SUSPECTED SIDE EFFECTS, contact Recordati Rare Diseases Inc. at 1-888-575-8344, or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before Taking SIGNIFOR LAR patients should tell their doctor about all of their medications. SIGNIFOR LAR may affect the way other medicines work, and other medicines may affect how SIGNIFOR LAR works. Especially tell your healthcare provider if you take medicines to control your heart beat (antiarrhythmics), medicines to control your blood pressure (beta-blockers or calcium channel blockers), medicines to control the potassium and magnesium (electrolytes) levels in your body, medicines that may affect the way the electrical system of your heart works (QT prolongation), cyclosporine, and bromocriptine.

Use in Specific Populations:

Females and Males of Reproductive Potential: Treatment with SIGNIFOR LAR may result in improved fertility and the possibility of unplanned pregnancy in females who have not gone through menopause. Talk to your healthcare provider about birth control methods that may be right for you during treatment.
It is not known if SIGNIFOR LAR is safe and effective for use in children.

Please see full Prescribing Information.

Please report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. You may also contact Recordati Rare Diseases Inc. at 1-888-575-8344 to report side effects.

Signifor

Patient support

Stay informed, connected, and supported
The R.A.R.E.^® program may help with financial assistance and more

STEPS TO TREATMENT SUCCESS

FINANCIAL ASSISTANCE

PHARMACIST FOLLOW-UP

NURSE EDUCATOR CHECK-IN

WORRY-FREE REFILL PROCESSING

Co-pay program

Home injection program

CONTACT THE R.A.R.E. PATIENT SUPPORT PROGRAM FOR ASSISTANCE

CONNECT WITH A PATIENT LIAISON (PL)

Your health journey is uniquely your own, but you’re not alone. As part of the Recordati Access, Resources, and Engagement (R.A.R.E.^®) family, you have access to a Recordati Rare Diseases PL to help you with your treatment along the way.

Indications and Usage

Important Safety Information:

Indications and Usage

Important Safety Information:

Patient support

Stay informed, connected, and supported The R.A.R.E.® program may help with financial assistance and more

STEPS TO TREATMENT SUCCESS

FINANCIAL ASSISTANCE

PHARMACIST FOLLOW-UP

NURSE EDUCATOR CHECK-IN

WORRY-FREE REFILL PROCESSING

Co-pay program

Home injection program

CONTACT THE R.A.R.E. PATIENT SUPPORT PROGRAM FOR ASSISTANCE

CONNECT WITH A PATIENT LIAISON (PL)

Your health journey is uniquely your own, but you’re not alone. As part of the Recordati Access, Resources, and Engagement (R.A.R.E.®) family, you have access to a Recordati Rare Diseases PL to help you with your treatment along the way.

Indications and Usage

Important Safety Information:

Indications and Usage

Important Safety Information:

Are you a Healthcare Professional?

Stay informed, connected, and supported
The R.A.R.E.^® program may help with financial assistance and more

Your health journey is uniquely your own, but you’re not alone. As part of the Recordati Access, Resources, and Engagement (R.A.R.E.^®) family, you have access to a Recordati Rare Diseases PL to help you with your treatment along the way.