Acromegaly is a hormonal disorder that generally develops when your pituitary gland produces too much growth hormone (GH) that then causes your liver to overproduce the hormone insulin-like growth factor 1 (IGF-1). This overproduction leads to changes in the body’s growth and development.
What causes acromegaly?
How common is acromegaly?
Acromegaly is a rare condition. In the US, there are approximately 71 to 88 cases per million people, and annually in the US, there are about 12 new cases per million people.
What are the signs and symptoms of acromegaly?
Some of the most common signs and symptoms of acromegaly include physical changes, such as enlarged hands and feet, changes in facial features (frontal bump, enlargement of the nose), snoring, and weakness/lack of energy.
How is acromegaly diagnosed?
Doctors will perform a biochemical screening as the first step toward diagnosing acromegaly. This screening is adjusted based on different characteristics in people.
How is acromegaly treated?
Doctors often recommend surgery as the initial treatment for the majority of patients. If surgery is not possible or has not improved your condition, your doctor may recommend drug treatment. SIGNIFOR® LAR (pasireotide) is an injection given by your doctor. If you and your doctor decide to continue treatment with SIGNIFOR LAR, it may lead to long-term reduction of your growth hormone levels.